Sessions Public -- LOVE this new spot in OB next door to the Catalina Lounge. Great local, slow-food kind of menu (loal produce, organic everything) and great craft beer selection. Kid-friendly but still feels cool and hip.
Analog -- Fun retro burger bar with burgers, totchos (tater tot nachos) and old-school games like pac man and live band karaoke.
Red Velvet -- Great little wine bar in Little Italon Fir at Kettner. Very International crowd and expensive wine list
Influx -- Now open in Little Italy. The best coffee shop + lunch place. Great sandches (I love the tuna) and cupcakes. Started in Golden HIll, now a second location the Q building in Little Italy.
Pho on Fifth -- New Pho spot in the heart of Hillcrest -- big space, lots of tables, good prices.