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Healthy Kids Magazine


Winter 2018

When it comes to

improving care,

there’s no substitute for

research. Lab scientists study

basic biology, looking for the

genetic and cellular variations

that drive disease. Translational

and clinical researchers

develop these discoveries into

new therapies. But before a

treatment is accepted, it must be

investigated thoroughly, often in

multiple clinical trials.

This is especially important

when treating children, who,

historically, have too often been

given medications that were

tested only on adults.

“The drug may function in

a different way or the dosing

strategy may be totally different.

You have to conduct the clinical

trials,” says Christina Chambers,

PhD, MPH, director of Clinical

Research at Rady Children’s and

a professor of pediatrics at UC

San Diego.

There are currently more than

150 clinical trials underway

at Rady Children’s that aim to

advance care for a wide variety

of conditions.

round 15 percent of young

children contract atopic

dermatitis, commonly known

as eczema. The condition pro-

duces rashes, profound itch-

ing, and bacterial infections

and can generate anxiety, depression, and

attention deficit hyperactivity disorder.

Rady Children’s and UCSD research-

ers created the first Eczema and

Inflammatory Skin Disease Center in

the country, and are leading a number of

international studies. Their hard work is

paying off.

“After no new drug approvals for ec-

zema since 2001, there are two first-in-

class medications approved in the last

few months,” says Lawrence Eichenfield,

MD, chief of pediatric and adolescent

dermatology at Rady Children’s and vice

chair of the Department of Dermatology

at UCSD. “A new type of medication,



for Eczema